Nurturing Immunity: Enhancing Immune competence in Neonatal Livestock in the Era of Antibiotic-Free Animal Farming
- Newborn's immune system is underdeveloped and immature immediately after hatching or birth, rendering them highly vulnerable to infectious threats present in the environment.
- Faster growth is likely to have a negative impact on the immune system thereby increasing the incidence of early mortality as well as threat of bacterial resistance.
- Banned the use of antibiotics in Animal production system, increased the demand for finding of alternate feed compounds along with a nutritious diet that can enhance gut health and immune function
Essential Role of Immunity Boosters for Broilers and Layers: Supporting Health and Productivity from Early Age to Maturity
Poultry production faces unique challenges in maintaining strong immune health in both broilers and layers. Immunity boosters are essential throughout their lifecycle to support health, productivity, and resilience against disease, particularly as the industry moves away from antibiotic use.
1. Early-Life Immunity for Health Foundation:
• Vulnerability in Young Chicks: Early life is a critical period for chicks as their immune systems are still developing. During this stage, they are exposed to new environments, potential pathogens, and environmental stressors. Immunity boosters help establish a strong immune foundation, reducing susceptibility to early-life diseases.
• Gut Health Development: Probiotics and prebiotics in early feed promote the development of beneficial gut bacteria, which is vital for immune health. A healthy gut is the first line of defense against pathogens and directly impacts the bird’s overall immunity and growth.
2. Ongoing Immunity Support for Broilers During Growth:
• Enhanced Disease Resistance: Broilers, bred for rapid growth, are prone to immune-related challenges due to metabolic stress and crowded conditions. Immunity boosters, such as yeast cell wall derivatives, beta-glucans, and essential vitamins (C and E), support a robust immune response, ensuring they can resist common pathogens.
• Reducing Dependency on Antibiotics: Strong immunity from an early age and during rapid growth reduces the need for antibiotics, aligning with sustainable, antibiotic-free production standards while minimizing the risk of antimicrobial resistance.
3. Long-Term Immunity in Layers for Health and Productivity:
• Consistent Egg Production: Layers need sustained immune support over a longer lifespan. Immune stressors, including nutritional fluctuations and environmental changes, can directly impact egg production and quality. Immunity boosters help reduce oxidative stress, improving both immune function and productivity.
• Reducing Infections in Reproductive Tract: Layers are susceptible to infections like E. coli and Salmonella that affect reproductive health and egg safety. Immunity-enhancing feed additives, including organic acids, trace minerals (like zinc and selenium), and plant extracts, help fortify immunity, reducing infection risks and maintaining flock health.
4. Enhanced Response to Vaccinations:
• Optimized Vaccine Efficacy: Immunity boosters support a better response to vaccinations by enhancing the body’s ability to produce antibodies. This is crucial for preventing outbreaks of infectious diseases that can cause high mortality and reduce productivity in both broilers and layers.
5. Improved Feed Efficiency and Growth:
• Immunity-boosting supplements, such as essential amino acids, minerals, and enzymes, enhance digestion and feed efficiency. This contributes to better growth rates in broilers and improved overall health in layers, supporting sustainable productivity.
What is Immuact?
Immuact
is a premium feed additive formulated to enhance the immunity, health and
performance of livestock. Combining the potent benefits of Beta glucans with a
proprietary blend of organic acids delivers functional components to support
livestock through everyday stress, transitions and disease challenges.
Benefits of Immuact:
- ·Boosting the Immune System and reduce disease incidence.
- ·Improves gut health by preventing colonisation of pathogens in gut.
- ·Reduced the diarrhea.
- ·Increases the liveability of birds
- ·Boosting Animal Performance Improves the body weight and FCR
- ·Increasing Antibody Titers after Vaccination.
- A valuable tool to the producer as an alternative to antibiotics.
Mode of action in Animals
1.Immune Modulation:
Immuact stimulate the immune system by activating macrophages, neutrophils, and natural killer cells, neutralised inflammatory cytokinin, leading to improved pathogen defence, thereby enhancing the animal's ability to fight infections. Nucleotides support rapid cell division and repair, crucial for the immune system. Propionic and butyric acids act as energy sources for intestinal cells and have anti-inflammatory properties, supporting immune health.
2. Antimicrobial Effect:
Beta glucans bind to pathogens, preventing their attachment to the gut lining, altering intestinal microbiota with competitive exclusion, while organic acids can lower gut pH, inhibit the growth of pathogenic bacteria in the gut, promoting a healthier microbiome.
3. Growth Promoter: Beta glucan promotes beneficial gut microflora and inhibits pathogens, while organic acids like fumaric and formic acid improve feed conversion by enhancing protein digestion and energy utilization. This combination can lead to better growth rates and feed efficiency.
4. Improved Nutrient Absorption: Glucans and mannan in yeast cell walls can bind to mycotoxins, reducing their absorption in the gut. Organic acids help in detoxifying the gut and maintaining a low pH, preventing the growth of toxin-producing moulds and bacteria. Enhances gut health by promoting SCFA, protect intestinal barrier function, improves tight junction, increase villus height crypt depth, leading to better digestion and nutrient uptake. Citric and lactic acids chelate minerals, enhancing their absorption in the gut. Organic acids reduce pH which activates secretion and activation of gastric and pancreatic enzymes leading better gut health, and better performance.
Research Trials:
According to the trial conclusively shows that Immuact supplementation at 1 kg/ton of feed offers significant advantages in broiler production. The observed improvements in mortality, body weight, and FCR, along with the economic benefits, support the recommendation of Immuact as a valuable feed additive for enhancing broiler performance and profitability.
Immuact
